- The invasive weed.
The not so mysterious plant is known under different names such as Mary thistle, milk thistle, etc. Silybum marianum has been grown as a medicinal plant in monastery gardens since ancient times. It belongs to the Asteraceae family. Nowadays this weed is again in the news for more health benefits.
- At a glance: advantages of milk thistle extracts.
Silibinin is the major bioactive component of sylimarin from the milk thistle plant. It has long been used for different illnesses. Silibinin has also been studied for its beneficial actions on many cancers.
1997: reduces hyperinsulinaemia, a condition in which there are excess levels of insulin circulating in the blood than expected; relative to the level of glucose.
2002: cancer letters journal shows that the natural compound can lessen lipid peroxidation in patients with alcoholic cirrhosis.
2010: cancer letters journal found that silibinin helps patients successfully take care of their disorder such as chronic hepatitis C.
2012: biochemical and biophysical research communications journal demonstrated that silibinin prevents and stops various inflammatory responses in the lungs like asthma.
2012: journal of cellular biochemistry confirmed that the compound restores bone formation and protect against skeletal illnesses like osteoporosis.
2012: journal of cellular biochemistry found that silibinin Inhibited and suppressed colorectal cancer.
2013: Milk thistle may restrict skin cancer growth. Researchers at The Hormel Institute have discovered that an anticancer agent in milk thistle significantly inhibits the growth of melanoma, a deadly form of skin cancer afflicting millions of people worldwide.
HIV patients manage hepatotoxicity related to highly active anti-retroviral drug therapy by taking milk thistle extracts.
2005: Interaction with drug.
Journal of clinical pharmacology uncovered that Milk thistle and indinavir do not interact.
milk thistle, scientific name silybum marianum.
Described in the first century AD by Dioscorides then by Pliny the Elder, milk thistle contains as a main constituent silymarin 70% to 80%. The lipophilic extracts from the seeds are composed of flavonolignans like silybin 50%, silychristin and silydianin. It is used for many illnesses. It is safe as well tolerated by patients.
- The plant reduces liver injury caused by acetaminophen, carbon tetrachloride, radiation, iron overload, alcohol, and amanita phalloides.
Liver damages and milk thistle.
- Chronic Alcohol consumption has been linked to many disorders such as liver cancer, causing 500 000 death every year.
- Chronic liver disease causes more than 25 000 deaths every year in USA.
- Liver failure ranks 10th as a cause of death. Alcohol use and viral hepatitis B and C are the most common factors.
Milk thistle is the most popular herbal supplement taken by patients suffering from liver diseases.
Colorectal cancer and milk thistle.
Colorectal cancer is the third most common form of cancer and the second cause of leading related death.
- Silibinin is one of the few botanic compounds demonstrating to have inhibiting effects on colorectal cancer stem cell like cell. It decreases tumor and inhibits growth.
Published in the journal of biochemical and biophysical research communications journal.
Lungs and silibinin.
Chronic airway inflammation and milk thistle.
Asthma, a widespread respiratory illness characterized by increased mucus production and infiltration of eosinophils.
- Silibinin attenuated allergic airway inflammation.
- It also reduces the levels of pro-inflammation and Th2 cytokines.
Published in 2012, biochemical and biophysical research communications .
Skeletal illnesses and skin melanoma lessen by silibinin.
- silibinin protect against bone loss.
- It also helps in bone formation.
- It promotes matrix mineralization by enhancing bone nodule.
Journal of cellular biochemistry.
2013: Milk thistle may restrict skin cancer growth.
Researchers at The Hormel Institute have discovered that an anticancer agent in milk thistle significantly inhibits the growth of melanoma, a deadly form of skin cancer afflicting millions of people worldwide